$16M NIH grant to map brain's wiring diagram

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$16M NIH grant to map brain's wiring diagram
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The University of Minnesota Medical School received a $16 million grant from the National Institutes of Health (NIH) Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative to support the groundbreaking project of unraveling the mysteries of the brain's 'wiring diagram.'

Reviewed by Danielle Ellis, B.Sc.Sep 26 2023 The University of Minnesota Medical School received a $16 million grant from the National Institutes of Health Brain Research Through Advancing Innovative Neurotechnologies® Initiative to support the groundbreaking project of unraveling the mysteries of the brain's 'wiring diagram.' Using cutting-edge techniques, this research aims to discover how the brain's neurons are connected and communicate with each other.

BRAIN CONNECTS follows in the footsteps of the Human Connectome Project. However, we're taking it further by using advanced MRI together with other emerging tools that rely on optical imaging and cell labeling techniques. This approach will provide us with a more detailed and much clearer picture of the brain's circuits.

Their goal is to create accurate wiring diagrams using a multi-modal, cross-species, multi-scale approach. This will provide crucial insights into brain connectivity and its impact on cognition, behavior and disease. The team of scientists involved in this project includes Damien Fair, PhD; Christophe Lenglet, PhD; Essa Yacoub, PhD at U of M Medical School; Taner Akkin, PhD at U of M College of Science and Engineering; Stamatios Sotiropoulos, PhD at University of Nottingham; Guoqiang Bi, PhD at Shenzhen Institute of Advanced Technology; Franco Pestilli, PhD at University of Texas Austin; Karla Miller, PhD and Saad Jbabdi, PhD at Oxford University; Kurt Schilling, PhD at Vanderbilt University; Partha Mitra,...

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