More than three years into the pandemic, and long COVID is still proving an elusive challenge to identify and treat. Why?
March, 15, 2023 – More than 3 years into the pandemic, finding out how many Americans have long COVID – and what to do about it – has proved to be far harder than identifying those infected with the virus who have recovered or died from it.
– including inflammation, autoimmunity, and immune dysfunction – and they hope that identifying biomarkers will make diagnosing the condition easier. Making matters more difficult is trying to parse whether certain symptoms, like anxiety or depression, are caused by the hardships of living through the pandemic, by a lingering COVID infection, or were preexisting in some people.
Post-COVID symptoms can also disappear and relapse, making the condition even more complex. Doing more longitudinal follow-up studies – which observe the same people over a period of time – may be the best way to identify cases like these because they can help researchers detect changes in both the individual and the group as a whole. But few longitudinal studies have been done on long COVID.
Another complicating factor: Many studies use self-reported surveys to gather information, a process that can also be rife with biases, inaccuracies, and other issues. Julia Moore Vogel, PhD, a program director with the Scripps Research Translational Institute, worries that the overall public health messaging – and lack of it on long COVID – may also be hindering efforts to combat it.
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