The new device speeds up the controls to secrete precious insulin. 🧐
With over 40 million people worldwide suffering the effects of type 1 diabetes, new efficient treatments are constantly in high demand. One technology that has great potential is the microencapsulation device , which houses insulin-secreting cells in a protective compartment protecting them from the body's autoimmune response.
Now, a team of researchers from Brigham and Women’s Hospital, Harvard University, and the University of Massachusetts Medical School designed a new convection-enhanced MED which continuously showers cells in nutrients that improve cell loading capacity, cell survival, glucose sensitivity, and timely insulin secretion,In initial trials, the ceMED showed a quick response to blood sugar levels only two days after being implanted.
"Overall, [the] results highlight significant advantages of ceMED over existing diffusion-based devices including improved cell survival, reduced fibrous encapsulation that can compromise functionality over time, and quicker on and off rates for insulin secretion," corresponding author Jeff Karp explained."This approach has the potential to enhance the success of β cell replacement therapies to help many T1D patients and their families manage this challenging disease.
The US-based team of researchers behind the new bioartificial pancreas says the prototype still needs a lot of work to be ready for mass production. If the device is eventually produced for the clinic, however, it has the potential to greatly improve treatment over current β cell replacement therapies and help sufferers of type 1 diabetes to manage the disease with greater ease.Stay ahead with the latest science, technology and innovation news, for free:
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