Researchers identify possible treatment targets to prevent antibiotic-induced hearing loss. Researchers at Indiana University School of Medicine are exploring new methods to investigate why an antibiotic causes hair cell death and permanent hearing loss in humans. In a study that was published i
In future studies, the proteins discovered in this work could be used as drug targets to prevent aminoglycoside-induced hearing loss.Researchers at
One of the primary causes of hearing loss in people is ototoxicity, or hearing loss brought on by medication. In the United States alone, hearing loss affects more than 48 million individuals. “As aminoglycosides specifically trigger a rapid localization change of RIPOR2 in hair cells, we hypothesize that RIPOR2 is essential for aminoglycoside-induced hair cell death,” Zhao said.
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