A kinase-cGAS cascade to synthesize a therapeutic STING activator - Nature

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A kinase-cGAS cascade to synthesize a therapeutic STING activator - Nature
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Nature research paper: A kinase-cGAS cascade to synthesize a therapeutic STING activator

This research used resources at the Industrial Macromolecular Crystallography Association Collaborative Access Team beamline 17-ID, supported by the companies of the Industrial Macromolecular Crystallography Association through a contract with Hauptman–Woodward Medical Research Institute. This research used resources of the Advanced Photon Source, a US Department of Energy Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under contract no.

Fuh-Rong Tsay, Xiaodong Bu, Benjamin F. Mann, Mirlinda Biba, Erik Guetschow, Erik Hoyt, Erik L. Regalado, Steve Castro, Nelo Rivera, Joseph P. Smith, Fengqiang Wang, Stephanus Axnanda & Zachary E. X. Dance

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