The original SARS-CoV-2 strain was found to bind to sialic acids (a class of sugars) on human cells, a trait not seen in later strains. This discovery, made by the Rosalind Franklin Institute and University of Oxford, offers insights into the virus's transmission and evolution, correlates with previ
Scientists discovered that the original SARS-CoV-2 strain could bind to sugars called sialic acids on human cells, a trait not retained by later strains such as Delta and Omicron. Utilizing high-resolution imaging and innovative analysis methods, they identified the binding mechanism’s location and investigated its evolutionary significance. This discovery has provided insights into viral transmission and potential zoonotic origin.
This binding was found using a combination of magnetic resonance and extremely precise high-resolution imaging, conducted at the Rosalind Franklin Institute and University of Oxford, and published recently in the journalThis unique ability in the early strain also raises the possibility that this is how the virus first transferred from animals to humans.
Professor Ben Davis of the Rosalind Franklin Institute and University of Oxford, one of the paper’s senior authors, said: “Two of the ongoing mysteries of the coronavirus pandemic are the mechanisms behind viral transmission and the origins of the zoonotic leap. As to why the virus has discarded the sugar-binding feature as it has evolved into new variants, Professor Davis hypothesizes that it may be necessary for the initial zoonotic leap into humans from animals but can then be hidden until it is required again – particularly if the feature is broadly detrimental to the virus’s mission of replication and infection within humans.The finding correlates with evidence from the first wave in Italy.
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
17-year-old arrested in Philadelphia in connection with terrorism probeA 17-year-old teenager in Philadelphia has been arrested in connection with a terrorism probe.
Weiterlesen »
Chris Noth Has a Personal Connection With Mental HealthThe actor, best known for his role as Mr. Big in “Sex and the City,” is the new face of Samuelsohn’s newly launched Iconics collection.
Weiterlesen »
Giants’ Daniel Jones-Darren Waller connection blossoming with huge practiceDaniel Jones completed his first 16 passes in team periods, including three touchdowns to TE Darren Waller.
Weiterlesen »
Man arraigned in connection to East Bay crime spreeA Pittsburg man was arraigned Monday in connection to a crime spree in the East Bay where he allegedly tried to carjack several people and tried to burglarize two homes.
Weiterlesen »
7 ‘Healthy’ Iced Tea Brands With More Sugar Than a Can of CokeDietitians say stay away from these store-bought bottled iced tea brands that have over 40 grams of sugar per serving.
Weiterlesen »
Narcissism and Emotional Neglect: The Surprising ConnectionChildhood emotional neglect can cause narcissism or excessive selflessness.
Weiterlesen »