The findings could enable early treatment.
Scientists hope that technology could eventually be used as a pre-screening tool forThe study was led by Moorfields Eye Hospital and the UCL Institute of Ophthalmology, with the team using AI to analyse an AlzEye dataset – a worldwide retinal imaging datavase – and pick up on retinal markers.
They looked at a cohort of 154,830 patients aged 40 and over who had attended secondary care ophthalmic hospitals inThe process was repeated using data from the UK Biobank, assessing 67,311 healthy volunteers aged between 40 and 69 who were recruited between 2006 and 2010.had a thinner ganglion cell-inner plexiform layer and inner nuclear layer in the eye, noting the change on average seven years before other symptoms appear.
Researchers suggest that looking at these layers in the years before symptoms present themselves could help detect the disease earlier. ‘I continue to be amazed by what we can discover through eye scans,’ said lead author Siegfried Wagner, a clinical research fellow at Moorfields and the UCL Institute of Ophthalmology researcher.
‘While we are not yet ready to predict whether an individual will develop Parkinson’s, we hope that this method could soon become a pre-screening tool for people at risk of disease.‘Finding signs of a number of diseases before symptoms emerge means that, in the future, people could have the time to make lifestyle changes to prevent some conditions arising, and clinicians could delay the onset and impact of life-changing neurodegenerative disorders.
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