During the COVID-19 pandemic, medical professionals and researchers observed that children and teenagers who contracted the virus exhibited milder symptoms compared to adults. This phenomenon may be attributed to the presence of memory T cells in children, which were generated as a result of previou
Researchers from Karolinska Institute found that children’s memory T cells generated by common colds can react to SARS-CoV-2, potentially explaining their milder COVID-19 symptoms. The memory T-cell response to coronaviruses was observed to develop as early as age two, with reactions being stronger earlier in life and weakening as individuals age.pandemic, medical professionals and researchers observed that children and teenagers who contracted theexhibited milder symptoms compared to adults.
“These reactions are especially strong early in life and grow much weaker as we get older,” says the study’s corresponding author Annika Karlsson, research group leader at the Department of Laboratory Medicine, Karolinska Institutet. “Our findings show how the T-cell response develops and changes over time and can guide the future monitoring and development of vaccines.”The results indicate that the memory T-cell response to coronaviruses develops as early as the age of two.
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