Researchers may have successfully converted stomach stem cells into insulin-producing cells, potentially offering a cure for diabetes
Imagine a future where patients with diabetes can produce their insulin, eliminating the need for daily injections. It would even mean eliminating diabetes as a disease itself.
Type 1 diabetes, which affects millions worldwide, is believed to be caused by an autoimmune response where the body mistakenly attacks and destroys the pancreas' beta cells responsible for insulin production. For years, scientists have been searching for a way to replace these lost cells using stem cells.
Early experiments in mice showed that ordinary pancreatic cells could be converted into insulin-secreting beta cells by activating three specific transcription factors, proteins that regulate gene expression. In 2016, Dr. Zhou and his team discovered that gastric stem cells responded well to this three-factor activation method.In the study, the researchers extracted gastric stem cells from human subjects using a non-surgical procedure called endoscopy.
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