Investigators have demonstrated 'excellent' results for detecting endometrial cancer in urine and cervicovaginal samples that women collect at home.
"Excellent diagnostic performances were maintained" in the 72 women with stage I endometrial cancer,"confirming the ability to detect endometrial cancer at its earliest stage," the investigators say.
Although the findings need to be validated in women presenting with postmenopausal bleeding as well as in asymptomatic women at risk for endometrial cancer, the at-home screening tests appear to have"great potential to noninvasively screen patient populations at risk for endometrial cancer," Wever and colleagues conclude.
For"most women with endometrial cancer, the bleeding will be painless; the symptom may be considered more of a nuisance and brushed off at first," Bakkum-Gamez said. Being able to conveniently screen at home"has the potential to truly improve survival in endometrial cancer through earlier detection and earlier intervention.", chief of gynecologic oncology at Columbia University, New York City, agreed that this at-home approach shows potential.
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