President Joe Biden on Monday nominated cancer specialist Dr. Monica Bertagnolli to become director of the National Institutes of Health
Dr. Monica Bertagnolli speaks at the University of California, San Francisco’s cancer center in San Francisco on Oct. 7, 2022.WASHINGTON — .
“Dr. Bertagnolli has spent her career pioneering scientific discovery and pushing the boundaries of what is possible to improve cancer prevention and treatment,” Biden said in a statement. She “will ensure NIH continues to be an engine of innovation to improve the health of the American people.”
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
CAR-NKT cell therapy: a new promising paradigm of cancer immunotherapy - Cancer Cell InternationalToday, cancer treatment is one of the fundamental problems facing clinicians and researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new therapeutic strategies are developed quickly. Adoptive cell therapy (ACT) is a practical approach that has been emerged to improve clinical outcomes in cancer patients. In the ACT, one of the best ways to arm the immune cells against tumors is by employing chimeric antigen receptors (CARs) via genetic engineering. CAR equips cells to target specific antigens on tumor cells and selectively eradicate them. Researchers have achieved promising preclinical and clinical outcomes with different cells by using CARs. One of the potent immune cells that seems to be a good candidate for CAR-immune cell therapy is the Natural Killer-T (NKT) cell. NKT cells have multiple features that make them potent cells against tumors and would be a powerful replacement for T cells and natural killer (NK) cells. NKT cells are cytotoxic immune cells with various capabilities and no notable side effects on normal cells. The current study aimed to comprehensively provide the latest advances in CAR-NKT cell therapy for cancers.
Weiterlesen »
Immunological and clinical implications of immune checkpoint blockade in human cancer - Archives of Pharmacal ResearchImmune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-CTLA-4 therapy are now FDA-approved treatment options for different cancer types. However, the therapeutic efficacy of ICIs varies substantially among cancer types and patients, and only a limited proportion of cancer patients benefit clinically from ICIs. To improve the therapeutic efficacy of cancer treatments involving ICI, the mechanisms of response to ICIs and the heterogeneous pattern of immune checkpoint receptor expression need to be better understood. Here, we review recent studies on ICIs in human cancer, providing the necessary basis for the rational design of immunotherapy and for appropriate patient selection.
Weiterlesen »
Single-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing - Genome MedicineEpigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for detecting and characterizing diseases such as cancer. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This approach generated up to 200 million reads for a single cfDNA sample from cancer patients, an order of magnitude improvement over existing nanopore sequencing methods. We developed a single-molecule classifier to determine whether individual reads originated from a tumor or immune cells. Leveraging methylomes of matched tumors and immune cells, we characterized cfDNA methylomes of cancer patients for longitudinal monitoring during treatment.
Weiterlesen »
Kidderminster & Oxford City reach National LeagueOxford City and Kidderminster Harriers reach the National League by winning their respective play-off finals.
Weiterlesen »
Monday's national newspaper front pages📰 What's on tomorrow's front pages? jonathansamuels is joined by Jasmine Cameron-Chileshe and Madeline Grant for the Press Preview . 📱 Watch live: 📺 Sky 501, Virgin 602, Freeview 233 and YouTube
Weiterlesen »
‘Emotional’ final reunion for teacher with terminal cancerIt was lovely that so many of Mr Sampey's former students went to see him and his art show. So many happy memories were shared ❤️
Weiterlesen »