CD19 CAR T-cell therapy and prophylactic anakinra in relapsed or refractory lymphoma: phase 2 trial interim results - Nature Medicine

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CD19 CAR T-cell therapy and prophylactic anakinra in relapsed or refractory lymphoma: phase 2 trial interim results - Nature Medicine
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Prophylactic use of anakinra, an IL-1 receptor inhibitor, reduced severe neurotoxicity incidence in patients with r/r lymphoma treated with anti-CD19 CARTcells immunotherapy jaeparkmd karthik_nath17 Michel_Sadelain MSKCancerCenter MSK_DeptOfMed

J.H.P. received consulting fees from Affyimmune Therapeutics, Amgen, Autolus, Be Biopharma, Beigene, Bright Pharmaceutical Services, Inc.

reports personal fees from Adicet, Allovir, Caribou Biosciences, Celgene, BMS, Equilium, Exevir, Karyopharm, Merck, MorphoSys, Omeros, Syncopation, VectivBio AG, Vor Biopharma, Cidara Therapeutics, Medigene, Sellas Life Sciences and NexImmune; personal fees and other support from Incyte, Kite/Gilead, Miltenyi Biotec, Nektar Therapeutics and Novartis; and other support from OrcaBio outside the submitted work. B.S. is an inventor on United States Provisional Patent Application No.

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