In a first-of-its-kind clinical trial, researchers used a cancer-killing cell therapy to successfully treat lupus in a small number of patients.
. At that time, they reported that a 20-year-old woman with a severe refractory SLE went into remission following the treatment.
"This is an exciting approach, but many more patients need to be treated to really understand the efficacy and safety," Belmont said. "The entire process must maintain sterility to avoid contamination, which would be harmful when reinfused into the patient," he said.According to Arthur Kavanaugh, MD, professor of medicine at UC San Diego Health, this form of therapy may be an option for severe refractory patients who have not responded well to other more established therapies.
The study authors say they intend to create a larger trial to further explore which type of patient may benefit the most from this treatment, and for how long.
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