Children who are sedentary for more than six waking hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood, a new study finds.
Jun 3 2024The Endocrine Society The research findings will be presented Saturday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass and published in Nature's npj Gut and Liver .
Fatty liver disease is a harmful fat buildup in the liver. When the condition is not due to alcohol consumption but linked to at least one of five components of metabolic syndrome, it is called metabolic-associated steatotic liver disease . For each half-hour of sedentary behavior above 6 hours per day, children had 15% higher odds of developing fatty liver disease before they were 25 years old. Any increase of sedentary time above 6 hours a day resulted in a corresponding decrease in the time spent in light-intensity physical activity, therefore 3 hours less daily by young adulthood.
However, he found that engaging in light-intensity physical activity for at least 3 hours a day reversed this premature liver damage. Each cumulative minute of moderate-to-vigorous physical activity in a day was associated with a slightly lower likelihood of severe MASLD at age 24 but was not associated with a lower likelihood of liver cirrhosis.
Adolescents Cancer Children Cirrhosis Endocrine Fatty Liver Hormone Liver Cancer Liver Disease Liver Transplant Obesity Ph Physical Activity Research Transplant Walking
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