Chiral gold nanoparticles increase vaccine efficacy by more than 25%, study suggests nature
Computational model of gold nanoparticle functionalized with left-handed enantiomers of cysteine and phenylalanine. Credit: André Farias de Moura
"The key to understanding the contribution of these nanoparticles is the concept of chirality, which applies to an object or system that can't be superimposed on its own mirror image," Moura told Agência FAPESP. Chirality is measured in"g-factor" on a scale from minus two to plus two . The procedure used in the study enabled the scientists to exceed 0.4 and resulted in three nanoparticles: the original achiral gold, the right-handed enantiomer, and the left-handed enantiomer.
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