COVID booster shots cut Omicron transmission in closed environments

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COVID booster shots cut Omicron transmission in closed environments
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COVID booster shots cut Omicron transmission in closed environments Omicron Coronavirus Disease COVID Vaccine NatureMedicine UCBerkeley UCBerkeley

Study: Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave. Image Credit: p.ill.i / Shutterstock

About the study In the present study, researchers analyzed SARS-CoV-2 surveillance data from 35 prisons in California, United States of America , between December 2021 and May 2022, a period that corresponded to the first five months of the COVID-19 wave when Omicron subvariants BA.1/BA.2 were predominant.

Study findings During the five-month study period, in a study population of 111,687 , there were 22,334 confirmed COVID-19 cases and 31 COVID-19-related hospitalizations. All participating California state prisons tested their residents for COVID-19 on average 8.1 times over the five-month study duration, with the average time between tests being 11.7 days.

In adjustment analyses, the Poisson regression model estimated that index cases vaccinated with ≥1 COVID-19 vaccine dose had, on average, a 22% lower risk of transmitting infection than unvaccinated index cases. Each additional dose further reduced the risk of transmission to close contact by an average of 11%.

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