Teams of scientists worldwide are racing to stay ahead of the next coronavirus by developing what's known as pan-coronavirus vaccines.
PHILADELPHIA — Her gloved fingers working quickly yet carefully, Garima Dwivedi filled row after row of little wells on a plastic laboratory plate, pushing a button to squirt drops of clear fluid she had extracted from the blood of mice.
People are also reading… In less than 20 years, at least three dangerous coronaviruses have jumped from animals to humans. Before the COVID-19 virus emerged in late 2019, there were SARS and MERS, each of which sickened thousands of people worldwide. A fourth new coronavirus, little known outside China, has so far been found only in pigs. But it's a grim one, having killed thousands of animals since 2016.
"Coronaviruses have caused three epidemics in the past 20 years," he said."We have to assume there will be more." Then came the delta variant, followed by omicron. The spike picked up a series of shape-shifting mutations that somehow allowed it pull off a double stunt: avoiding recognition by the antibodies, yet still fitting the lock well enough to open the door.In Weissman's lab at Penn, Dwivedi was testing mice for their response to one of them: a viruslike particle that contains both the spike and other structural proteins.
In most cases, these spillovers appear to fizzle out, says Ken Field, a Bucknell University biologist who studies the immune system of bats. The virus may have picked up the ability to jump from animal to human, but not the ability to make copies of itself inside the person — nor the ability to be transmitted from that person to the next.
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