Dame Deborah James raised almost £6.8m for research into new cancer treatments. Experts say 'it is 'one of the most fundamental breakthroughs in cancer medicine' in recent decades
'From what the doctor said, I should not be alive right now"
When her aggressive bowel cancer was first diagnosed it had already spread to her liver, and she was given just three years to live at most. The drugs Sophie took - Ipilimumab and Nivolumab - are a type of immunotherapy. These drugs, which boost or change how the immune system attacks cancer, have proven so successful in her and in some other patients that they haveA new way to think about cancer
The mutation meant the disease was in some ways more obvious to her immune system - our bodies own in-built defence systems - then other tumours can be.This guided doctors towards a type of personalised treatment called immunotherapy. One of the immunotherapy drugs she took, Ipilimumab, helped, though a series of steps, to turn on her immune response, allowing special immune cells called T cells to be activated.
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