Comment: Decision makers need constantly updated evidence synthesis
of COVID-19 research. The system can be applied beyond COVID-19, and indeed beyond health. Here’s what that will take.The process of identifying and combining data across studies to create a clear understanding of a body of research is known as evidence synthesis. The resulting publications are generally called systematic reviews, and often include a meta-analysis.
Evidence synthesis can be applied to the most pressing global challenges: climate change, energy transitions, biodiversity loss, antimicrobial resistance, poverty eradication and so on. But in practice, synthesis projects are often under-resourced, of poor quality, uncoordinated, duplicative and out of date.
Even with a deluge of new research, it is feasible to update syntheses and treatment guidelines frequently. For COVID-19, we pushed that limit lower than ever, updating some living guidelines weekly . Frequent updating assured policymakers and the public that all relevant research had been taken into account when recommending against the use of the drug hydroxychloroquine, for example.
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