Detection of unreported infections based on SARS-CoV-2 antibody seroprevalence Antibody Coronavirus COVID SARSCoV2 LancetRH_Americ CDCgov QuestDX Labcorp
By Dr. Priyom Bose, Ph.D.Dec 12 2022Reviewed by Benedette Cuffari, M.Sc. In the United States, the severe acute respiratory syndrome coronavirus 2 , the causal agent of the ongoing coronavirus disease 2019 pandemic, was first detected in late January 2020. Since then, several COVID-19 waves have occurred due to the emergence of highly infectious SARS-CoV-2 variants, such as B.1.617.2 and B.1.1.529 .
A new The Lancet Regional Health study analyzed data from all cross-sectional, national, repeated, and all-aged SARS-CoV-2 seroprevalence studies to elucidate the nationwide temporal trends of COVID-19 prevalence. The main aim of this study was to determine the overall antibody seroprevalence trends in different subgroups based on age, sex, and urbanicity. Additionally, the authors analyzed changes in the serological estimates at different phases of the pandemic and across geographical areas.
The authors obtained additional data, including the sex, age, state, ZIP code, and specimen collection dates. However, the study did not include vaccination status, race, and ethnicity. The lowest seroprevalence was found in people aged 65 years or older. Both males and females exhibited similar infection-induced seroprevalence estimates.
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