A study in Nature Medicine reveals that diabetes accelerates the onset of multiple long-term conditions by 15-20 years, significantly reducing life expectancy in English adults.
By Dr. Sushama R. Chaphalkar, PhD.Reviewed by Susha Cheriyedath, M.Sc.Aug 4 2024 In a recent study published in the journal Nature Medicine , researchers in the United Kingdom estimated the onset age, number of years spent, and life loss in diabetes-related multiple long-term conditions among 46 million English adults. They found that diabetes accelerated the onset of severe MLTCs by 15–20 years, significantly reduced life expectancy , and varied in impact across age groups.
Background Type 2 diabetes significantly contributes to various forms of morbidity due to insulin resistance, chronic hyperglycemia, and related dysfunctions. It is strongly associated with both microvascular and macrovascular complications, including cardiovascular, eye, foot, and kidney diseases.
The prevalence of diabetes with MLTCs was estimated. A three-state illness-death Markov model was then used to estimate the years people spend with and lose due to these conditions. Key metrics were determined, including lifetime risk, median age of onset, years lived with the conditions, age at death, and years of life lost, considering both individual and community perspectives.
Related StoriesThe median onset age for at least two conditions was found to be 66–67 years, with persons observed to develop more conditions experiencing earlier death and fewer years with MLTCs. Younger adults with MLTCs were found to face a greater impact on life years spent and lost.
Life Expectancy Asthma Cancer Chronic Coronary Heart Disease Depression Eye Foot Healthcare Heart Heart Disease Hyperglycemia Insulin Insulin Resistance Kidney Medicine Mental Health Osteoarthritis Respiratory Respiratory Disease Type 2 Diabetes
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