Does Stress Activate or Suppress the Immune System?

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Does Stress Activate or Suppress the Immune System?
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Stress activates the inflammatory part of the immune system while suppressing the illness-fighting part, making us more susceptible to getting sick.

A stressful situation triggers a natural immune response, producing inflammation in the body.The stress literature can feel confusing. You hear from one source that stress suppresses the immune system, making it easier to get sick. Then you read from another that stress makes the immune system go into overdrive, causing systemic inflammation and increased risk of negative health outcomes like cardiovascular disease and autoimmune disorders.

In our hunter-gatherer days, we would stress when under physical attack or at risk of getting kicked out of the clan. Our natural immune system would kick in to help us heal if we got injured or exposed to an unknown pathogen, which could happen if we wandered through the wilderness alone.

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