What Is Nootkatone? EPA Approves Natural Grapefruit Compound to Repel Insects
that nootkatone kills biting pests “in a unique way, different from other insecticides already registered by the EPA, including pyrethroids, organophosphates, carbamates, and cyclodienes.”found that volunteers who stuck a hand coated in nootkatone into a container of hungry mosquitoes found that the substance had “good repellent activity” and “exceptional mosquitocidal effects at very low concentrations.
The researchers wrote that the reason for this is unclear, but theorized that nootkatone may block receptors on the insects’ nerve cells for the neurotransmitter octopamine, making the insects hyperactive. “It causes fatal spasms,” Alan says.Nootkatone isn’t available yet, but the EPA’s registration of the ingredient means that it can now be used to develop new insect repellents and insecticides.
“It has great potential,” Alan says. “From the data so far, it seems like a good product, but time will tell.”
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