In a recently published article featured on the cover of the Biophysical Journal, Dr. Rafael Bernardi, assistant professor of biophysics at the Department of Physics at Auburn University, and Dr. Marcelo Melo, a postdoctoral researcher in Dr. Bernardi's group, shed light on the transformative capabilities of the next generation of supercomputers in reshaping the landscape of biophysics.
Illustration of a protein placed over a computer chip. New, powerful computers are helping scientists design and understand proteins like never before. Credit: Rafael C. Bernardi, Dr. Rafael Bernardi, assistant professor of biophysics at the Department of Physics at Auburn University, and Dr. Marcelo Melo, a postdoctoral researcher in Dr. Bernardi's group, shed light on the transformative capabilities of the next generation of supercomputers in reshaping the landscape of biophysics.
The researchers at Auburn delve into the harmonious fusion of computational modeling and experimental, providing a perspective for a future in which discoveries are made with unparalleled precision. Rather than being mere observers, today's biophysicists, with the aid of advanced high-performance computing , are now trailblazers who can challenge longstanding biological assumptions, illuminate intricate details, and even create new proteins or design novel molecular circuits.
One of the most important aspects discussed in their perspective article is the new ability of computational biophysicists to simulate complexAs Dr. Bernardi articulates,"The new exascale computers allow computational biophysicists to go beyond what can done experimentally and simulate biological processes with a much higher level of detail.
Historically, fields such as physics and chemistry have relied heavily on theoretical models to guide experiments.
The momentum gained by computational biophysics signifies a monumental shift. As biophysical research progresses, the seamless integration of experimental and computational efforts is expected to redefine the frontiers of knowledge, laying the groundwork for unprecedented discoveries that could reshape our understanding of the biological world.Marcelo C.R.
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