FDA approves Eli Lilly’s Zepbound, a weight loss drug similar to Ozempic and Wegovy

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FDA approves Eli Lilly’s Zepbound, a weight loss drug similar to Ozempic and Wegovy
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Berkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.

The Food and Drug Administration on Wednesday approved Zepbound, a new weight loss drug from drugmaker Eli Lilly that was shown in clinical trials to help people lose up to 52 pounds in 16 months. Zepbound is the latest entrant into the field of powerful new drugs that already includes Novo Nordisk's Ozempic and Wegovy and Lilly's Mounjaro. The FDA approved the drug for adults with obesity or who are overweight with at least one weight-related condition.

“When I’m talking to a patient, I’m going to discuss both of them,” he said. The new drug, like others in its class, comes with side effects including gastrointestinal problems. Dr. Daniela Hurtado Andrade, an endocrinologist at the Mayo Clinic, said that while gastrointestinal issues are very common with GLP-1 medications, most of the side effects will not affect a person’s quality of life.

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