Pictures shared on social media showed huge flames coming from the building.
Firefighters are still tackling the aftermath at Clarendon Leisure Centre on Liverpool Street, Pendleton.
In a further statement, GMFRS added: "Firefighters are currently tackling a fire involving a leisure centre off Liverpool Street in Salford. Residents nearby should keep windows and doors closed and people are asked to avoid the area while crews deal with the incident." Councillor John Warmisham, who represents Pendleton and Charlestown ward, said news of the fire was 'very upsetting'.
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