A new study led by Rutgers University has highlighted the potential of innovative techniques in understanding and studying mental disorders. A new study led by scientists at Rutgers University has uncovered new insights into the underlying brain mechanisms of autism spectrum disorder (ASD). The stu
Autism, also known as Autism Spectrum Disorder , is a complex developmental disorder that affects communication, social interaction, and behavior. It is characterized by difficulties in verbal and nonverbal communication, social interactions, and repetitive behaviors.
The research team used cutting-edge techniques, including growing human brain cells from stem cells and transplanting them into mouse brains, to make these discoveries.Describing the study in the journal,, researchers reported a mutation – R451C in the gene Neurologin-3, known to cause autism in humans – was found to provoke a higher level of communication among a network of transplanted human brain cells in mouse brains.
Autism spectrum disorder is a developmental disability caused by differences in the brain. About 1 in 44 children have been identified with the disorder, according to estimates from the Centers for Disease Control and Prevention. Researchers employed CRISPR technology to alter the human stem cells’ genetic material to create a line of cells containing the mutation they wanted to study, and then derived human neuron cells carrying this mutation. CRISPR, an acronym for clustered regularly interspaced short palindromic repeats, is a unique gene-editing technology.
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