Genetic Mutation May Explain Why Some Women Struggle to Breastfeed

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Genetic Mutation May Explain Why Some Women Struggle to Breastfeed
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“Screening for this variant and combining that with maternal reports and characteristics could help identify moms and babies that may need additional support.”

moms exclusively breastfeed until baby is six months old, as this helps give baby the nutrition they need and boosts their immune system.

However, not every mom is able to do this—and it could be for a myriad of reasons including a lack of supply, pain, it doesn’t work with her schedule or she simply doesn’t want to. While all of these are legitimate reasons to stop breastfeeding, one study is finding that, for women who have an inadequate milk supply, a genetic mutation may be to blame.. It looked at perceived inadequate milk supply , which is a condition in which women stop breastfeeding because their supply wasn’t enough.

The researchers also collected DNA samples in the form of saliva from the mothers. They analyzed 18 genes that frequently occurred in milk-producing tissue in women, looking for mutations within them to find if there was an association with PIMS. While they found 10 modifications in the genes, there was one variant found more frequently in women who suffered from PIMS.

According to Dr. Steven Hicks, lead researcher and pediatrician at Penn State Health Children’s Hospital, 83 percent of women start breastfeeding, but only 57 percent continue until their child is 6 months old. “Socioeconomic and environmental factors may contribute to early cessation, but milk supply is also an often-cited reason.

While more research is needed and the findings need to be proven with a larger sample size, Hicks is hopeful this work will help new mothers meet their breastfeeding goals. “Moms with this mutation still produce milk, even if it may be less than women without the mutation, but challenges like poor diet, hydration or sleep could be enough to hinder the supply that they do have,” he said.

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