Iain Henderson will start in Ireland's vital World Cup game against Scotland on Saturday as hooker Dan Sheehan is also drafted in.
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The other change from the win over the Springboks sees hooker Dan Sheehan take over from Ronan Kelleher.Ulster centre McCloskey has not featured in the World Cup so far but is preferred among the replacements to Keith Earls and Jimmy O'Brien for the Stade de France contest. Back row Jack Conan is in line for his first outing since damaging foot ligaments two months ago after being named in the replacements.
Ireland will top the group - and likely set up a mouth-watering quarter-final against New Zealand - if they avoid defeat or lose by seven points or fewer.Captain Johnny Sexton admits Ireland's final Pool game with Scotland feels like it is a knockout match."We have spoken about that and that is why it is important that we get our preparation right, and we need to go out and get our performance right now.
"It is a huge game. We have Iain Henderson in our group. He is good at maths so he is across everything as far as that is concerned.Watch: Ireland 'wary' of 'incredibly threatening' Scots - Henderson
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