'Grave Consequences': Scientists Warn of Extreme Bias in Brain Aging Research

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'Grave Consequences': Scientists Warn of Extreme Bias in Brain Aging Research
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Instead, male anatomy is too often considered 'the norm' against which all other human brains are measured.to call out the prevailing sex bias in neuroscience research, but their report is incredibly comprehensive, spotlighting the numerous ways in which sex hormones might impact healthy brain aging.

The female risk for depression, for instance, is highest during a person's reproductive years, while the risk for Alzheimer's increases after menopause, when the hormone estradiol These hormones are 'master regulators' of the human body, impacting the immune system, metabolism, vascular function, bone maintenance, and brain function.

Adolescence, for instance, is marked by a shift in sex hormone concentrations, as well as substantial changes in the brain, and an increased risk of depression.Nevertheless, studies on the relationship between depression arising from phases of endocrine transition and Alzheimer's disease risk are lacking.

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