Is medical cannabis treatment associated with improvements in health-related quality of life? JAMANetworkOpen Swinburne medical cannabis medicalcannabis weed legal qualityoflife qol QOL health
By Pooja Toshniwal PahariaMay 11 2023Reviewed by Lily Ramsey, LLM In a recent study published in JAMA Network Open, researchers investigated whether cannabis treatment could improve the health-associated quality of life over time in Australia.
Given the vast range of medical conditions being treated with medical cannabis and the wide array of products and dosages available, cannabis as a medicine is becoming increasingly prevalent. The main study outcome was improving health-associated QoL, evaluated using the 36-component Short Form Health Survey questionnaire.
Results Among 3,148 participants, the mean age was 56 years; 1,688 were female, and 820 were employed. Individuals received cannabis treatment most frequently for chronic pain , cancer pain , anxiety , and insomnia . The most commonly used medications were simple analgesics , opioid analgesics , antidepressants , benzodiazepines , and gamma-aminobutyric acid analogs .
For balanced therapy, equivalent CBD and THC doses of 19 mg were prescribed daily. For cannabidiol-dominant therapy, the mean CBD and THC doses were 97 mg and 9.0 mg, respectively, and for tetrahydrocannabinol-dominant therapy, the corresponding doses were 5.0 mg and 36 mg, respectively.
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Stress, coping, and quality of life in the United States during the COVID-19 pandemicWhile research has widely explored stress, coping, and quality of life (QOL) individually and the potential links between them, a critical dearth exists in the literature regarding these constructs in the context of the COVID-19 pandemic. Our study aims to identify the salient stressors experienced, describe the coping strategies used, and examine the relationships between stressors, coping, and QOL among individuals during the pandemic. Data are from a sample of 1,004 respondents who completed an online survey. Key measures included stressful life events (SLEs), coping strategies, and the physical and psychological health domains of QOL. Staged multivariate linear regression analyses examined the relationships between SLEs and the two QOL domains, controlling for sociodemographic and pre-existing health conditions and testing for the effects of coping strategies on these relationships. The most common SLEs experienced during the pandemic were a decrease in financial status, personal injury or illness, and change in living conditions. Problem-focused coping (β=0.42, σ=0.13, p | 0.001 for physical QOL; β=0.57, σ=0.12, p | 0.001 for psychological QOL) and emotion-focused coping (β=0.86, σ=0.13, p | 0.001 for psychological QOL) were significantly related to higher levels of QOL, whereas avoidant coping (β=–0.93, σ=0.13, p | 0.001 for physical QOL; β=-1.33, σ=0.12, p | 0.001 for psychological QOL) was associated with lower QOL. Avoidant coping partially mediated the relationships between experiencing SLEs and lower physical and psychological QOL. Our study informs clinical interventions to help individuals adopt healthy behaviors to effectively manage stressors, especially large-scale, stressful events like the pandemic. Our findings also call for public health and clinical interventions to address the long-term impacts of the most prevalent stressors experienced during the pandemic among vulnerable groups.
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