Drs Kathy Miller and Harold Burstein discuss new breastcancer data presented ASCO22 as well as antibody-drug conjugates.
, shifting from triple-negative breast cancer to ER-positive/HER2-negative breast cancer, as conventionally defined, and again, comparing against standard chemotherapy drugs.I would say for sure. Here, there was improvement in progression-free survival. It went from around 4 months to 5.5 months, so not a huge gap. Clearly, it's an active drug, but at the moment, it doesn't look like a game changer in the same way that the trastuzumab deruxtecan does.
You're a journal editor, so you'll yell at me for doing this, but if you sort of eyeball these things side to side, trastuzumab deruxtecan looks like a far more active drug. In fact, it's probably the most active drug we have now in triple-negative breast cancer, as well as other subtypes.If we focus on the hazard ratios, there was much greater improvement with trastuzumab deruxtecan.
, which was a long-term follow-up of another study of ovarian suppression, a high-risk group of patients who got chemotherapy but remain premenopausal. Now, with close to 10 years of follow-up, there is a 5% absolute difference favoring ovarian suppression in terms of preventing recurrence of breast cancer, underscoring the point that ovarian suppression remains an active treatment approach. It clearly brings more side effects for younger women.
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
City Hall, Gov. Kathy Hochul to negotiate details of NY class size bill: Eric AdamsMayor Eric Adams confirmed that City Hall is in negotiations with Gov. Kathy Hochul regarding a costly class-size reduction bill passed by the state Legislature.
Weiterlesen »
Carl Paladino Announces Plan to File Pro-2A Lawsuit Against Gov. Kathy HochulGOP congressional candidate Carl Paladino announced his plan to file a lawsuit against Gov. Kathy Hochul (D) and other New York Democrats regarding their new gun control law limiting concealed carry.
Weiterlesen »
Kathy Bates and Michael Mann Pay Tribute to James Caan: ‘What a Terrible and Tragic Loss’“Jimmy was not just a great actor with total commitment and a venturesome spirit, but he had a vitality in the core of his being that drove everything from his art and friendship to athletics and very good times,' Michael Mann said of James Caan
Weiterlesen »
Kathy Hochul makes green push with data-gathering hybrid cars, energy efficient buildingsAs she runs for a full term in office, Gov. Kathy Hochul is pushing data-gathering hybrid cars in a green push for New York City that also includes more energy efficient buildings.
Weiterlesen »
Gov. Kathy Hochul signs legislation requiring private space for breastfeeding in airportsThe new bill requires New York airports to provide a space for breastfeeding away from public view.
Weiterlesen »
Governors Kathy Hochul and Phil Murphy sign $14B funding agreement for Gateway Hudson Tunnel projectNew York and New Jersey reach funding agreement for phase 1 of Gateway Project to build two rail tunnels under Hudson River. elijahwestbrook reports:
Weiterlesen »