A groundbreaking study has identified nearly 300 previously unknown genetic variants linked to depression, nearly doubling the known number of DNA patterns associated with the condition. The research, which analyzed genetic data from over 5 million adults worldwide, offers new hope for developing targeted treatments for this prevalent mental health disorder.
Scientists have made a significant breakthrough in understanding and predicting depression risk by identifying nearly 300 previously unknown genetic variants associated with the condition. This groundbreaking research, led by experts from the United Kingdom, has nearly doubled the known number of DNA patterns linked to depression, bringing the total to over 697 variants.
The study, which analyzed genetic data from over 5 million adults across 29 countries, offers new hope for developing targeted treatments for depression.The findings, published in the journal Cell, highlight the complex interplay of genetics and depression. While each genetic variant has a small effect on an individual's risk, the cumulative impact of multiple variants can significantly increase susceptibility. The researchers emphasize that this discovery paves the way for personalized medicine approaches to depression treatment. Importantly, this research included individuals from diverse ethnic backgrounds, including African, East Asian, Hispanic, and South Asian descent, addressing the limitations of previous studies that primarily focused on European populations. This broader representation provides a more comprehensive understanding of the genetic factors contributing to depression across different populations. The identification of these genetic variants opens up possibilities for repurposing existing drugs, such as Pregabalin (used for chronic pain) and Modafinil (used for narcolepsy), as potential treatments for depression. However, further research and clinical trials are necessary to validate these findings and explore the efficacy and safety of these repurposed medications
GENETICS DEPRESSION MENTAL HEALTH RESEARCH TREATMENT DRUGS
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Study uncovers how cancer builds molecular bridges to evade the immune system'Build your enemy a golden bridge to retreat across' is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War.
Weiterlesen »
Study uncovers aspartate's surprising role in lung metastasesResearchers from the lab of Prof. Sarah-Maria Fendt (VIB-KU Leuven) and colleagues have uncovered that the availability of the amino acid aspartate is one reason why the lung is a frequent organ of metastasis.
Weiterlesen »
Hospital Begins 'World-Leading' Study Testing Hundreds of Babies for Rare Genetic ConditionsA hospital in Leeds has launched a groundbreaking study testing hundreds of babies for over 200 rare genetic conditions. The study, a collaboration between Genomics England and NHS England, aims to identify conditions in asymptomatic babies through whole genome sequencing using blood samples from the umbilical cord. Parents will be informed about the study during pregnancy and can choose to participate. The study hopes to enable earlier diagnosis and treatment for babies with treatable genetic conditions.
Weiterlesen »
Liam Payne autopsy uncovers devastating details about star's final momentsA preliminary autopsy into the death of former One Direction star Liam Payne has been released, and it has confirmed the tragic circumstances surrounding his death at the age of 31
Weiterlesen »
Century-Old Visitors' Book Uncovers History of Southampton's Mayflower TheatreA hotel visitors' book from 1928 has unearthed fascinating details about the inaugural production at Southampton's Mayflower Theatre. The book, donated to the theatre's archive, contains signatures from performers involved in the first show, 'Winona,' and provides insights into their stay at a local guest house.
Weiterlesen »
Woman chases phone snatchers down and uncovers their ‘secret’ hiding spotIzzy Du was walking along a busy main road in north London when two people on a bicycle snatched her mobile.
Weiterlesen »