Link between aldehydes and premature aging revealed

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Link between aldehydes and premature aging revealed
AldehydesDNADNA Damage
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A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging.

Apr 12 2024Nagoya University Published in Nature Cell Biology, their findings reveal insights into premature aging diseases and potential strategies to combat aging in healthy individuals such as controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.

For healthy individuals, ALDH2 is also important in our response to alcohol. When a person drinks wine or beer, the liver metabolizes the alcohol into aldehydes so it can be eliminated from the body. The activity of ALDH2 is important for converting the aldehydes into a non-toxic substance. Related StoriesThese processes are important because they are related to the clearance of aldehydes. It suggests an association between premature aging diseases and aldehyde accumulation.

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