Spaceflight was also found to be linked to DNA mutations. A groundbreaking study from the Icahn School of Medicine at Mount Sinai found that astronauts are more likely to develop mutations, potentially connected to spaceflight, that raise astronaut's lifelong risk of acquiring cancer and heart dise
The researchers believe it is important to continuously screen the blood of astronauts throughout their careers and during their retirement in order to monitor their health.Icahn School of Medicine at Mount Sinai
Somatic mutations are mutations that occur after conception and in cells other than sperm or egg cells, meaning they cannot be passed on to children. The mutations uncovered in this study were characterized by an excess of blood cells produced from a single clone, a process known as clonal hematopoiesis .
The study subjects were astronauts who flew relatively short space shuttle missions between 1998 and 2001. Their median age was approximately 42 years old; roughly 85 percent were male, and six of the 14 were on their first mission. The researchers collected whole blood samples from the astronauts 10 days before their flight and on the day of landing, and white blood cells only three days after landing. The samples were stored at -80ºC for approximately 20 years.
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