Long-term exposure to e-cigarette vapor that contains nicotine greatly increased the risk of tumor growth, according to a yearlong study in mice.
serves as a stark reminder that it’s too soon to know whether e-cigarettes are a safe alternative to smoking.
In addition, the researchers found that 23 of the 40 mice that inhaled the vapor with nicotine developed bladder hyperplasia, an out-of-control cell reproduction in the lining of the bladder that often precedes cancer. That compares with 1 out of 16 mice that inhaled vapor without nicotine and zero out of 17 mice that breathed filtered air.
“We can’t say that e-cigarettes definitively cause human cancer, but the mechanism at play here is very clear: The same carcinogens are being produced that other studies have shown cause human cancer,” Tang said. “We can extrapolate that, with e-cigarettes, you’ll cause damage in your genetic material, and damage your cells — and that will accumulate the longer you smoke.”
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