Professor Jian Feng of the Jacobs School of Medicine and Biomedical Sciences told Newsweek: 'This will enable the generation of human cells, tissues or even organs in animals.'
said he was most surprised that his team were able to produce lots of human red blood cells for reasons that are unclear. This shows that the human stem cells developed faster in the mouse embryos, as such cells would not be found in a human embryo until after about seven to eight weeks, he explained.
The study also showed how the team were able to turn stem cells from a primed to naïve state in order to grow the different cells. While naïve cells aren't on track to become a specific type of cell, primed stem cells are on the path to developing into a specific type of cell. They did this by inhibiting an enzyme in primed human stem cells for three hours. This enabled the newly naïve human stem cells to grow with naïve mouse cells in the. The technique previously used to create naïve human stem cells wasn't able to create human cells of different types in mouse embryos.
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