Mini-brains show how common drug freezes cell division in the womb, causing birth defects

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Mini-brains show how common drug freezes cell division in the womb, causing birth defects
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Minibrains show how common drug freezes cell division in the womb, causing birth defects

Valproic acid — a drug commonly used to treat epilepsy and bipolar disorder — can cause birth defects and developmental disorders if taken during pregnancy, but the reason why has long been a mystery.

Now, in a study using mice and human tissue, scientists discovered that the medication locks some embryonic cells into a suspended state where they can't properly grow or divide. By forcing key stem cells cells into this state, called senescence, valproic acid may disrupt brain development…

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