Ryan Jewell's family described the 28-year-old as a 'kind and caring soul'
A man described as a "model prisoner" was found dead in his cell after being refused permission to move to an open prison.
As he had been given a sentence of indeterminate imprisonment for public protection, Mr Jewell had no release date scheduled and so would have to apply to the parole board to be released or re-categorised. He had already served the minimum jail term for his sentence at the time of his death. One month after Mr Jewell was refused permission to move to an open prison, an officer was conducting their check of D Wing at 5.26am on January 9 when they found him unresponsive in his cell. Paramedics were called but Mr Jewell was pronounced dead.
Miss Richardson said her brother had an "infectious laugh" and would be sorely missed. She highlighted the impact of his death on their mother.
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A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes - BMC BiologyBackground The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer similarity to humans in these aspects, compared to the widely used Mus musculus and Rattus norvegicus models, holds the promise of better translation of research findings to the clinic. Results We report a 2.5 Gb, chromosome-level reference genome assembly with fully resolved parental haplotypes, generated with the Vertebrate Genomes Project (VGP). The assembly is highly contiguous, with contig N50 of 11.1 Mb, scaffold N50 of 83 Mb, and 95.2% of the sequence assigned to chromosomes. We used a novel workflow to identify 3613 segmental duplications and quantify duplicated genes. Comparative analyses revealed unique genomic features of the Nile rat, including some that affect genes associated with type 2 diabetes and metabolic dysfunctions. We discuss 14 genes that are heterozygous in the Nile rat or highly diverged from the house mouse. Conclusions Our findings reflect the exceptional level of genomic resolution present in this assembly, which will greatly expand the potential of the Nile rat as a model organism.
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