Moderna starts trial on omicron-specific Covid booster in adults

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Moderna starts trial on omicron-specific Covid booster in adults
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NEW: Moderna announces it has begun a clinical trial testing an omicron-specific Covid-19 vaccine booster.

, show about a sixfold drop in the ability of the antibodies to neutralize the omicron variant, compared with the original strain, six months after the booster.

The company's announcement comes a day after Pfizer and BioNTech announced that they started a clinical trial testing their own modified vaccine targeting theThe extremely contagious variant now accounts for virtually all new cases of Covid in the United States, according to theModerna is enrolling two groups in its clinical trial: People who received two doses of its vaccine at least six months ago, and people who received two doses plus a booster shot at least three months ago.

The company said it expects to enroll approximately 300 participants into each arm of the trial, which will be conducted at up to 24 sites in the U.S. Bill Hanage, an epidemiologist at the Harvard T.H. Chan School of Public Health, said Moderna's trial will allow scientists to know how much of a benefit there is in training the immune system to attack the new variant.

"The decline in neutralizing antibodies against omicron that they report six months post booster is enough to allow the virus to start an infection, but the immune response is still strong enough to handle it pretty well in the great majority of people," he said.it is in discussions with public health leaders about potentially distributing an omicron-based booster in the fall.

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