Researchers have developed a new test that can accurately measure biological aging in a clinical setting. The discovery was made while studying patients for the aging effects of chronic kidney disease.
A team of European researchers has developed a new test that can accurately measure biological aging in a clinical setting. The discovery was made while studying patients for the aging effects of chronic kidney disease.
The research team studied more than 400 patients with chronic kidney disease in Sweden alongside around 100 matched population controls, to better understand the impact on ageing of the disease, including during dialysis treatment and after kidney transplant. To do this, researchers used a range of tests including blood biomarkers, skin autofluorescence and epigenetic clocks.
To address this, the team developed a new, more accurate epigenetic clock -- the Glasgow-Karolinska Clock -- that works on healthy and unhealthy tissue. The results from this new clock matched what doctors saw in patients with chronic kidney disease, and also appeared to accurately assess healthy tissue too. This study is the first real-world test of epigenetic clocks in a normal ageing setting, and against clinical parameters.
"Methylation tagging of DNA is impacted by what we eat and also out gut microbiome. As a result, this new clock has real potential to be able to evaluate lifestyle interventions, including diet, that could benefit the public and help to address issues such as health inequalities."
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
UAF researchers confirm increase of salmon spawning in arctic riversAn increase of salmon spawning in arctic rivers provides leads researchers to question why the increase is happening.
Weiterlesen »
Researchers reconstruct speech from brain activity, illuminates complex neural processesResearchers created and used complex neural networks to recreate speech from brain recordings, and then used that recreation to analyze the processes that drive human speech.
Weiterlesen »
Removal of magnetic spacecraft contamination within extraterrestrial samples easily carried out, researchers sayBy demonstrating that spaceflight doesn’t adversely affect the magnetism of moon rocks, researchers underscore the exciting potential of studying the magnetic histories stored in these samples.
Weiterlesen »
Researchers' analysis of perching birds points to new answers in evolutionary diversificationWhen Charles Darwin traveled to the Galapagos Islands almost 200 years ago as a gentleman naturalist, he used the power of observation to develop his theory that species evolve over time.
Weiterlesen »
Researchers monitor emissions from Africa’s Copperbelt mines from spaceNo 1 source of global mining news and opinion
Weiterlesen »
Researchers model cell behavior called 'coiling' to understand cancer dynamicsIn any fight, knowing your enemy is critical to staging a defense. The fight to stop cancer or to accelerate wound healing is no exception. The research teams at Virginia Tech and the Weizmann Institute of Israel, along with partners worldwide, are pursuing a deeper understanding of how cells move and spread throughout a living body.
Weiterlesen »