Nasal vaccine to prevent COVID-19 passes first tests NatureMicrobiol
that is administered through the nose. In the latest issue of the journal, the interdisciplinary team describes how this live attenuated vaccine confers better immunity than vaccines injected into muscle.
"Nasal vaccines are far more effective in this regard than injected vaccines, which fail or struggle to reach the mucous membranes," says Dr. Emanuel Wyler, another co-last author. He has been researching COVID-19 since the start of the pandemic as part of the RNA Biology and Posttranscriptional Regulation Lab, which is led by Professor Markus Landthaler at the Berlin Institute for Medical Systems Biology of the Max Delbrück Center .
The co-first author draws attention to one of the observations the team made during their study:"We were able to show that prior intranasal vaccination results in the increased reactivation of these local memory cells in the event of a subsequent SARS-CoV-2 infection. Needless to say, we were particularly pleased with this result.
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