A squirt up the nose could reduce coronavirus transmission, but the vaccines have challenges to overcome. COVID19 COVID pandemic Vaccinations CovidIsNotOver
The prospect of having nasal vaccines that may be able to curb transmission better than existing shots is understandably exciting. But these types of vaccines still have a way to go before hitting local pharmacies or doctors’ offices.
First, it’s crucial for the nasal vaccines to strike the right balance. Their sprays must be strong enough to provoke our immune systems, but still weak enough that there aren’t unwelcome symptoms or side effects. It’s also of course important to ensure the safety of vaccine candidates that include live, weakened viruses.
Some nasal vaccine candidates are similar to the influenza vaccine and include live, weakened viruses. Most of these viruses aren’t the coronavirus itself, but rather harmless-to-human viruses that sport one coronavirus protein for our bodies to recognize. Others may not need a virus to grow in the body to work. One team is developing a nasal spray that includes only the coronavirus spike protein, which helps the virus break into cells.
Second, nasal sprays face the same problem as current COVID-19 vaccines. What happens when the virus evolves in ways that help it hide from our immune system? We’ve already seen the consequences of that thanks to the delta and omicron waves that raced around the globe. And from 2016 to 2018, FluMist. Experts recommended that people get a different type of flu shot in those seasons.
If I had a choice, I would never catch coronavirus. But in the grand scheme of things, it’d be nice if a spray up my nose could drastically lower my chances of passing it on to someone else if I did get infected. If they make it to consumers, the nasal vaccines could make future COVID-19 waves much smaller than they are now.
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