Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone.
Baylor College of Medicine Oct 8 2024 Triple-negative breast cancer is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone. They experience worse outcomes than patients with other breast cancer subtypes – their five-year mortality rate is about 40%.
Previous studies in the lab have shown that targeting kinases can be effective therapeutically in other cancers. There are many inhibitors of these enzymes that are already approved by the Food and Drug Administration for human use that could be tested for their potential therapeutic value in TNBC. Related StoriesIt's important to highlight that while the protein levels of DAPK3 were higher than normal in TNBC, the levels of its precursor mRNA were not. The mRNA molecule carries the genetic sequence of the DAPK3 gene and is used by the cell to synthesize the protein. "Many studies only rely of mRNA data to assess what proteins are produced by cells," Wang explained.
Cancer Cell Gene Kinase Laboratory Medicine Mortality Protein Research
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Northampton Market returns home after £10m faceliftThe historic market has new stalls from Italy, new paving, new lighting and new trees.
Weiterlesen »
Huawei’s new Mate XT is the first triple-folding smartphone on the marketJonathan Bell has written for Wallpaper* magazine since 1999, covering everything from architecture and transport design to books, tech and graphic design. He is now the magazine’s Transport and Technology Editor. Jonathan has written and edited 15 books, including Concept Car Design, 21st Century House, and The New Modern House.
Weiterlesen »
Man Arrested in New York for Triple Homicide in VermontBrian Crossman Jr., 22, has been arrested in New York on charges of being a fugitive from justice in connection with the murders of his father, stepmother, and stepbrother in Pawlet, Vermont. Vermont State Police say they have 'significant evidence' linking Crossman Jr. to the killings.
Weiterlesen »
Man Arrested In New York On Murder Charges Connected To Vermont Triple HomicideBrian Crossman Jr., 22, of Granville, New York, has been arrested on charges of being a fugitive from justice in connection with the triple homicide of his father, stepmother, and stepbrother in Pawlet, Vermont.
Weiterlesen »
Man Arrested In New York On Aggravated Murder Warrant For Triple Homicide In VermontBrian Crossman Jr., 22, of Granville, New York, has been arrested on a fugitive from justice charge after an arrest warrant was issued for him by the Vermont State Police on three counts of aggravated murder.
Weiterlesen »
New Fabulous Bingo players can triple their first deposit and get 100 free spins...
Weiterlesen »