New insights into lipid-induced senescence in dopaminergic neurons

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New insights into lipid-induced senescence in dopaminergic neurons
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A new research perspective was published in Aging (listed by MEDLINE/PubMed as 'Aging (Albany NY)' and 'Aging-US' by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, 'Lipid accumulation drives cellular senescence in dopaminergic neurons.

Aging -USAug 13 2024 A new research perspective was published in Aging " and " Aging -US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

In their perspective, researchers Taylor Russo and Markus Riessland from Stony Brook University found that artificially inducing GluCer accumulation leads to cellular senescence of DA neurons. This suggests that lipid aggregation plays a crucial role in the pathology of PD by driving senescence in these vulnerable neurons.

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