New Research Reveals How Plant-Derived Nutrients Can Affect the Gut and Brain

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New Research Reveals How Plant-Derived Nutrients Can Affect the Gut and Brain
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Science, Space and Technology News 2023

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The interventional study led by the University of Leipzig Medical Center indicates that consumption of high-dose dietary prebiotics leads to a reduction in reward-related brain activation in response to high-calorie food stimuli. “The results suggest a potential link between gut health and brain function, in this case, food decision-making,” says PD Dr Veronica Witte, co-author of the study and a scientist at the University of Leipzig Medical Center.

The MRI examination was repeated at four time points, before and after the prebiotic administration and before and after a placebo phase in which the participants were given a preparation with identical energy density but without prebiotics. When the participants evaluated high-calorie foods, there was comparatively less activation of reward-related brain areas after they had consumed the prebiotic fiber. This effect was accompanied by a shift in the composition of the gut bacteria.

“Further studies are needed to investigate whether treatments that alter the microbiome could open up new avenues for less invasive approaches to the prevention and treatment of obesity. A better understanding of the underlying mechanisms between the microbiome, gut, and brain could help to develop new strategies that promote healthier eating habits in people at risk” says Dr Witte.

Reference: “Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial” by Evelyn Medawar, Frauke Beyer, Ronja Thieleking, Sven-Bastiaan Haange, Ulrike Rolle-Kampczyk, Madlen Reinicke, Rima Chakaroun, Martin von Bergen, Michael Stumvoll, Arno Villringer and A Veronica Witte, 4 October 2023,SciTechDaily: Home of the best science and technology news since 1998.

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