The study found that Moderna had greater rates of heart inflammation than Pfizer, although the overall risk remained extremely low. In comparison to the Pfizer BioNTech COVID-19 vaccine, the Moderna Spikevax COVID-19 vaccine has a two- to three-fold greater incidence of myocarditis, pericarditis, o
The study found that Moderna had greater rates of heart inflammation than Pfizer, although the overall risk remained extremely low.vaccine, the Moderna Spikevax COVID-19 vaccine has a two- to three-fold greater incidence of myocarditis, pericarditis, or myopericarditis following a second dose; nonetheless, overall cases of heart inflammation with either vaccine are very rare.
In all, more than 2.2 million second Pfizer doses were given and more than 870,000 Moderna doses. Within 21 days of the second dose, there were a total of 59 myocarditis cases and 41 pericarditis cases . Researchers also looked at rates per million doses and the rate was 35.6 cases per million for Moderna and 12.6 per million for Pfizer—an almost threefold increase after Moderna shots vs. Pfizer. Comparatively, rates of myocarditis in the general population in 2018, were 2.
“Few population-based analyses have been conducted to directly compare the safety of the two mRNA COVID-19 vaccines, which differ in important ways that could impact safety,” said Naveed Janjua, MBBS, DrPH, lead author of the study and an epidemiologist and the executive director of Data and Analytic Services at the British Columbia Centre for Disease Control.
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