Katalin Karikó and Dr. Drew Weissman won the 2023 Nobel Prize in medicine for their work on mRNA vaccines.
The 2023 Nobel prize in physiology or medicine has been awarded to two scientists who developed the messenger RNA vaccine technology used in the first effective shots against COVID-19.
"mRNA vaccines, together with other COVID-19 vaccines, have been administered over 13 billion times," Rickard Sandberg, a member of the Nobel committee for physiology or medicine and the Royal Swedish Academy of Sciences, said during the committee's announcement on Monday."Together [the two prize winners] have saved millions of lives, prevented severe COVID-19, reduced the overall disease burden, and enabled societies to open up again.
To get around this, in the 1980s scientists began looking at more efficient ways of getting cells to make the required proteins. One method, called in vitro transcription, worked by generating mRNA directly inside cells in culture. In the early pandemic, this helped scientists to rapidly produce mRNA vaccines that acted against the coronavirus's"spike" protein — a pointy protein on the germ's surface. —'Face blindness' could be rare long COVID symptom, case report hintsThe research has also opened the door for work on potential cancer vaccines and for the rapid development of vaccines in response to possible future viral threats, such as bird flu, the Nobel committee said in its announcement.
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