Novavax coronavirus vaccine induces immune response in early study, shares jump

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Biotechnology company Novavax said its vaccine candidate produced higher levels of antibodies in healthy volunteers after two doses than those found in recovered COVID-19 patients, raising hopes for its eventual success

- Novavax Inc said on Tuesday its experimental COVID-19 vaccine produced high levels of antibodies against the novel coronavirus, according to initial data from a small, early-stage clinical trial, sending the company’s shares up 10%.

Maryland-based Novavax said its vaccine candidate, NVX-CoV2373, produced higher levels of the antibodies in healthy volunteers after two doses than those found in recovered COVID-19 patients, raising hopes for its eventual success. Effective vaccines and treatments are considered essential to halting a pandemic that has claimed more than 695,000 lives worldwide.

The trial, which started in late May, tested the vaccine in 106 subjects aged 18 to 59 versus a placebo. The Phase I study looked at the vaccine’s safety and ability to induce immune responses. Headache, fatigue, and muscle pain were among the more common side effects, and the vaccine was “well tolerated” overall, the company said.

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