Oral Immunotherapy Shows Promise for Adult Food Allergy

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Oral Immunotherapy Shows Promise for Adult Food Allergy
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Almost two thirds of adults completing an oral immunotherapy regimen for milk, peanut, sesame, egg, or tree nuts achieved full desensitization in the largest adult OIT cohort to date.

Almost two thirds of adults completing an oral immunotherapy regimen for milk, peanut, sesame, egg, or tree nuts achieved full desensitization in the largest adult OIT cohort to date, researchers from the Shamir Medical Center Allergy Clinic in Zerifin, Israel and the Sackler School of Medicine, Tel Aviv University, reported in a"Our experience from over a decade of oral immunotherapy, treating many adults, shows favorable outcome and safety profile for non-milk allergens," lead...

The OIT program at Shamir Medical Center is ambulatory and begins with a 3-4 day dose-escalation phase in which the single highest tolerated dose is determined for each patient. This dose is then consumed once daily at home for 24 days, with further up-dosing and home treatment phases in which the dose can be escalated up to fourfold.

More than half of the adult cohort were treated for milk allergy, while 5.2% were treated for egg allergy, 18.8% for peanut, 7.3% for sesame, and 13.5% for tree nuts.

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